Transposon mutagenesis for discovery of disease causing genes and their cooperative interactions in acute myeloid leukemia [ 2013 - 2015 ]

Research Grant

Researchers: Dr Stephan Glaser (Principal investigator) ,  Dr Ian Majewski ,  Dr Wei Shi ,  Prof Donald Metcalf

Brief description The emergence of cancer is caused by multiple mutations in normal cells. Recent progress has allowed the detection of virtually all mutations in a cancer genome. Although this has been enormous progress, it has become increasingly evident that only rare mutations are responsible for sustained tumour growth and treatment failure, while the majority of mutations are without effect. Our research will assist identification of the genetic changes essential to leukemia development, which will help develop new cancer therapies.

Funding Amount $AUD 659,302.00

Funding Scheme Project Grants

Notes Standard Project Grant