[Cite as http://purl.org/au-research/grants/nhmrc/1150083]
Prof Patrick Sexton
Prof Arthur Christopoulos
Prof Christos Pantelis
Prof Robert Parton
Brief description Membrane proteins are the principal gatekeepers for control of cellular response, with G protein-coupled receptors (GPCRs) the largest family of cell surface proteins. These proteins are critically important for pathophysiological control, and are a major target for drug discovery. Nonetheless drug attrition due to lack of clinical efficacy remains high. We are combining cell biology, clinical management and drug discovery science to enable more effective therapeutic translation.
Funding Amount $AUD 9,466,000.00
Funding Scheme Program Grants