Transgenerational impacts of paternal stress on offspring mental health: Epigenetic mechanisms and therapeutic interventions [ 2015 - 2017 ]

Research Grant

Researchers: Prof Anthony Hannan (Principal investigator) ,  A/Pr Timothy Bredy ,  Dr Terence Pang

Brief description We are following up the extraordinary, almost ‘Lamarckian’, discovery that environmental influences on fathers can affect their offspring via ‘epigenetic’ changes to the sperm. We will explore mechanisms whereby increased levels of paternal stress can cause behavioural changes in the offspring, which are relevant to depression and anxiety disorders, and how positive environmental factors, including physical activity, may induce beneficial effects. This will have major public health implications.

Funding Amount $AUD 572,941.81

Funding Scheme Project Grants

Notes Standard Project Grant