Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/GNT1127750]Researchers: Prof Murray Whitelaw (Principal investigator) , Prof Ismaa Farooqi , Prof Michael Cowley
Brief description Specific gene regulatory proteins define functions of various subsets of neurons in the hypothalamus. We will determine how interactions between three such proteins activate the leptin-melanocortin pathway, a hypothalamic signalling circuit that controls appetite. Defects in these proteins are found in obese patients who suffer from excessive eating disorders. The project will improve understanding of the genetic determinants of obesity and provide key points for development of new therapies.
Funding Amount $586,704.00
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : GNT1127750
- PURL : https://purl.org/au-research/grants/nhmrc/GNT1127750