[Cite as http://purl.org/au-research/grants/nhmrc/543141]
Prof Steve Gerondakis
Prof Frances Shannon
Brief description An unfortunate consequence of immune function is that occasionally rogue immune cells are produced that attack the host and lead to the development of so-called autoimmune diseases such as arthritis. Normally a white blood cell called a regulatory T cell suppresses these self reactive immune cells. We have identified factors that govern genetic programs in regulatory T cells. Understanding how these factors work should permit the development of new strategies to combat autoimmune diseases.
Funding Amount $AUD 492,991.29
Funding Scheme NHMRC Project Grants
Standard Project Grant