grant

Transcription control of the c-fms gene [ 2005 - 2007 ]

Also known as: Relationships between production of white blood cells and cancer progression

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/351559]

Researchers: Prof David Hume (Principal investigator) ,  Prof Susan Clark

Brief description This project concerns the basic biology of large white blood cells called macrophages. Macrophages are required for the immediate defence against infection, wound repair and normal turnover of tissues, but they can also produce toxic products that cause illness, especially in inflammatory diseases and cancer. We are studying a gene that is normally only produced in macrophages, but appears abnormally in many cancer cells. Our aim is to understand at a molecular level exactly how the gene is controlled, and why it appears in tumours.

Funding Amount $AUD 666,000.00

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857