grant

Transcription at the centromere: roles in formation, maintenance and function [ 2010 - 2012 ]

Also known as: How is the central structure that controls proper chromosome separation formed?

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/607317]

Researchers: Dr Paul Kalitsis (Principal investigator) ,  Prof Andy Choo (Principal investigator) ,  A/Pr Lee Wong Dr Owen Marshall

Brief description Every human has 46 chromosomes. Chromosomes are structures that carry genes in all our cells. The centromere is an essential component of a chromosome which governs the process of cell division and separation of replicated chromosomes. Defects in centromere function cause abnormalities in cell division that in turn cause a variety of genetic diseases including cancer. We propose to investigate the role that transcription at the centromere plays in determining correct centromere function.

Funding Amount $AUD 549,092.56

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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