TLR9 AGGRAVATES GLOMERULONEPHRITIS AND KIDNEY INJURY IN RENAL VASCULITIS [ 2012 - 2014 ]

Research Grant

Researchers: Dr Shaun Summers (Principal investigator) ,  Prof Arthur Kitching (Principal investigator)

Brief description Renal failure is a significant cause of morbidity and mortality in Australia. Anti-neutrophil cytoplasmic antibody (ANCA) vasculitis associated glomerulonephritis (GN) is a significant cause of renal failure. The molecular mechanisms underlying ANCA vasculitis are poorly understood, while treatments are associated with considerable morbidity and mortality. This grant aims to explore key molecular events involved in the disease pathogenesis to facilitate the use of safer more targeted therapies.

Funding Amount $AUD 349,336.38

Funding Scheme Project Grants

Notes New Investigator Grant