Tissue specific antigen presenting cell functions during infection. [ 2010 - 2012 ]

Research Grant

Researchers: Dr Christian Engwerda (Principal investigator) ,  Prof Paul Kaye

Brief description T cell activation is often inefficient following infection or vaccination, resulting in poor control of pathogens. In this grant, we propose to investigate the cellular basis for sub-optimal CD4+ T cell activation following infection. Specifically, we will study the roles of antigen presenting cells in CD4+ T cell activation in an experimental model of visceral leishmaniasis caused by the human protozoan parasite Leishmania donovani.

Funding Amount $AUD 555,325.32

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant