How do thick airway walls affect airway hyperresponsiveness in asthma? [ 2008 - 2011 ]

Research Grant

Researchers: Prof Gregory King (Principal investigator) ,  Dr Cheryl Salome ,  Dr Nathan Brown ,  Prof Norbert Berend

Brief description Asthmatic airways narrow too easily, a characteristic called airway hyperresponsiveness (AHR). To understand the cause of asthma we need to understand the cause of AHR. Thickened airway walls could amplify airway narrowing and increase AHR. However, thick airway walls are also stiff, and stiff walls could reduce narrowing and AHR. This project will examine the relationships between AHR and airway wall thickness and stiffness during and after treatment that reduces airway wall thickness.

Funding Amount $AUD 382,538.81

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant