Therapeutic implications of a molecular link between survivin and telomerase reverse transcriptase [ 2009 - 2012 ]

Research Grant

Researchers: Dr Karen Mackenzie (Principal investigator) ,  Prof Maria Kavallaris ,  Prof Richard Lock

Brief description A unifying feature of all types of cancer cells is that they are immortal. Our investigations will build upon our recent results that showed the gene survivin is involved in cancer cell immortalisation. We will characterise a molecular link between survivin and the enzyme telomerase, which is central to cancer cell immortality. Furthermore, we will demonstrate the therapeutic potential of turning off both survivin and telomerase as a novel approach to halting the growth of cancer cells.

Funding Amount $AUD 547,970.74

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant