The evolution of bacterial pathogenesis: a genomic approach [ 2008-01-01 - 2013-04-01 ]

Research Grant

Researchers: Associate Professor Scott Beatson (Australian Research Fellowship) ,  Associate Professor Scott Beatson (Australian Research Fellowship)

Brief description The evolution of bacterial pathogenesis: a genomic approach. The outcome of this research will be a better understanding of the genes involved with adaptation to particular pathogenic lifestyles. Specifically, genes that are rapidly evolving in selected bacterial pathogens of medical and veterinary importance will be identified using a bioinformatics approach that exploits the existence of multiple closely-related genome sequences. Such genes encode potential new targets for therapeutic intervention that provide alternatives in the face of emerging antibiotic resistance. Importantly, the methodology developed in this project is broadly applicable to the study of evolution of bacterial pathogenesis in any background: medical, agricultural or horticultural.

Funding Amount $503,686

Funding Scheme Discovery Projects

View this grant in the ARC Data Portal