The bacterial type IX secretion system in polymicrobial dysbiosis and chronic inflammation [ 1/1/2021 - 12/31/2025 ]

Research Grant

Brief description Periodontitis (severe gum disease) affects 1 in 3 adults and has been linked with heart attacks, cancer and dementia. I will lead a multidisciplinary team investigating the interaction between disease causing bacteria in the mouth and the immune response which results in destruction of the tooth’s supporting tissues and allows bacteria to enter the blood stream. The expected outcome is the development of a novel therapy which will stop progression of disease associated with these pathogens.

Funding Amount $1,900,000

Funding Scheme Investigator Grants

Chief Investigator Prof Eric Reynolds

Notes Leadership 3