TGFbeta isoforms differentially regulate fibrosis and inflammation in diabetic nephropathy via KLF transcription factors [ 2008 - 2010 ]

Research Grant

Researchers: Prof Carol Pollock (Principal investigator) ,  A/Pr Xin-Ming Chen ,  Dr Weier Qi

Brief description Progressive scarring and inflammation in the kidney represent the final common injury pathway for diseases that lead to kidney failure, including diabetic nephropathy. This project explores the interplay between the molecular processes that are triggered by high glucose levels in patients with diabetic nephropathy, some of which are deleterious and some potentially 'protective'. By understanding these mechanisms we will be able to prevent and more effectively treat kidney disease in diabetes.

Funding Amount $AUD 540,639.38

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant