TGF-beta/Smad signalling in macrophage-mediated renal fibrosis. [ 2017 - ]

Research Grant

Researchers: A/Pr David Nikolic-Paterson (Principal investigator) ,  Dr Frank Ma ,  Prof Hui Lan

Brief description Scarring of organs such as the kidney, lung or liver is a common mechanism leading to organ failure and death. We postulate that a type of white blood cell (the macrophage) can transition into the cell type (the fibroblast) responsible for making the excess collagen that leads to this scarring. If proven, this will be a major advance in our understanding of organ fibrosis and may identify new therapeutic approaches to currently intractable diseases.

Funding Amount $683,739.00

Funding Scheme Project Grants

Notes Standard Project Grant