grant

Tetraspanins serve as molecular facilitators to regulate platelet thrombus formation [ 2010 - 2012 ]

Also known as: Physiological regulators of platelet thrombus formation

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/603812]

Researchers: Prof Denise Jackson (Principal investigator) ,  A/Pr Mark Wright Prof Leonie Ashman

Brief description Platelets are small fragments of megakaryocytes that circulate in the blood stream. They play an important role in preventing excessive blood loss at sites of tissue injury by sticking together and forming a haemostatic plug. Excessive platelet clumping in diseased blood vessels can lead to blockages and cause thrombotic diseases such as heart attack and stroke. We have discovered that tetraspanins serve to regulate platelet glycoproteins including integrin alphaIIbbeta, P2Y12 and thrombosis.

Funding Amount $AUD 589,544.75

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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