Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1009231]Researchers: Prof Roger Reddel (Principal investigator) , A/Pr Hilda Pickett
Brief description The continuing growth of cancers depends on their cells being able to prevent shortening of chromosome ends (telomeres). Some cancers, including very aggressive brain and connective tissue tumours, achieve this via the Alternative Lengthening of Telomeres (ALT) process. We have evidence that the telomere structure of normal cells prevents ALT. Here we will examine how the telomere structure of ALT-positive cancer cells is changed, and whether reversing these changes inhibits ALT.
Funding Amount $AUD 522,122.10
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1009231
- PURL : https://purl.org/au-research/grants/nhmrc/1009231
