Targetting Monocytes With Microparticles To Prevent Kidney Allograft Rejection [ 2016 - 2019 ]

Research Grant

Researchers: Prof Steven Chadban (Principal investigator) ,  A/Pr Huiling Wu ,  Dr Daniel Getts ,  Prof Nicholas King

Brief description Whilst transplantation is lifesaving for many Australians with organ failure, it is a treatment rather than cure as recipients are dependent upon lifelong immunosuppression to prevent transplant rejection. Risks of death due to infection and cancer therefore remain high. We will test a new strategy in mice which modifies recipients of monocytes at the time of transplantation, to enable them to accept and tolerate the organ without ongoing need for expensive and dangerous immunosuppressive drugs.

Funding Amount $AUD 997,798.48

Funding Scheme Project Grants

Notes Standard Project Grant