Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/GNT1160323]Brief description TWEAK/Fn14 signalling critically regulates inflammation, fibrosis and liver progenitor cell responses - all processes involved in progressive chronic liver injury. In this study, we will now define the involved cell populations, identify the underlying mechanisms and test pharmacological targeting of this pathway as a novel therapeutic avenue to inhibit chronic liver disease progression to cancer. Importantly, we will also assess translatability of our findings into the human setting.
Funding Amount $997,486.00
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : GNT1160323
- PURL : https://purl.org/au-research/grants/nhmrc/GNT1160323
