Targeting Tregs Using Chimeric Antigen Receptors (CARs) for the Treatment of Autoimmune Renal Disease [ 2015 - 2018 ]

Research Grant

Researchers: Dr Yuan Min Wang (Principal investigator) ,  Dr Yiping Wang ,  Prof Stephen Alexander

Brief description Chronic Kidney Disease is one of the major causes of death in Australia. Therapeutic success with regulatory T cells (Tregs) capable of targeting autoimmune kidney disease would have major clinical implications. In the proposed study, we will use Chimeric Antigen Receptors (CARs) T cells by redirecting them to diseased organs, protect against kidney injury. These CAR T cells will recognise renal antigens and target immune cells and antibodies to limit kidney damage.

Funding Amount $AUD 845,519.92

Funding Scheme Project Grants

Notes Standard Project Grant