Targeting Tau phosphorylation to treat and prevent acquired epilepsy, neurodegeneration and neuropsychiatric disease following a brain injury [ 2011 - 2013 ]

Research Grant

Researchers: Prof Terence O'Brien (Principal investigator) ,  A/Pr Nigel Jones ,  Prof Christopher Hovens ,  Prof Dennis Velakoulis

Brief description This project will explore a new approach to the prevention and treatment of epilepsy and the associated mental health disorders following a brain injury. This involves inhibiting pathological forms of the Tau protein, which has been implicated in the development of epilepsy and neurodegeneration. The drug that will be tested in this study has already been demonstrated to be safe and well tolerated in humans, meaning that a positive result from these studies could be expediently translated into clinical studies.

Funding Amount $AUD 524,820.33

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant