Targeting redox homeostasis to prevent Mycobacterium tuberculosis persistence [ 2018 - ]

Research Grant

Researchers: Dr Chris Greening (Principal investigator)

Brief description Tuberculosis is now the leading cause of death from infectious disease worldwide. This reflects the ability of its causative agent to persist, leading to failure of antibiotic treatment and development of drug resistance. In this project, we propose to overcome this by inhibiting a unique metabolic pathway that is activated when the pathogen enters its persistent state. We will use a cutting-edge combination of techniques to develop this pathway for next-generation therapies.

Funding Amount $396,025.00

Funding Scheme Project Grants

Notes New Investigator Grant