Targeting the NLRP3 inflammasome and interleukin-18 in hypertensive heart failure [ 1/1/2021 - 12/31/2024 ]

Research Grant

Brief description Heart failure is a common complication of hypertension and a major cause of death and disability worldwide. This project will characterise a newly identified inflammatory pathway that we believe to be a major cause of the enlargement and scarring of the heart that accompanies hypertension. We will also trial drugs that block this inflammatory pathway to determine their suitability as future therapies for this devastating disease.

Funding Amount $1,241,115

Funding Scheme Ideas Grants

Chief Investigator Prof Grant Drummond

Notes Ideas Grants