Targeting neutrophil extracellular traps to reduce inflammation in severe asthma [ 2017 - 2019 ]

Research Grant

Researchers: Dr Katherine Baines (Principal investigator) ,  Prof Jodie Simpson ,  Prof Peter Gibson ,  Prof Vanessa Mcdonald

Brief description People with severe asthma, a chronic disease of the lungs, often have many inflammatory cells in the airways called neutrophils. Neutrophils release a meshwork of fibers in a web like trap called NETs, which are made of the cells DNA and other proteins that fight infection. These NETs can promote inflammation in the persons airways. Current asthma treatments have no effect on NETs. This project will measure NETs in the airways and test a new treatment to reduce NETs, and relieve asthma symptoms.

Funding Amount $AUD 607,498.64

Funding Scheme Project Grants

Notes Standard Project Grant