grant

Targeting the mitochondrial transcriptome to treat mitochondrial disease [ 2013 - 2015 ]

Also known as: Engineered proteins as treatments for mitochondrial disease

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1045677]

Researchers: A/Pr Oliver Rackham (Principal investigator) ,  A/Pr Aleksandra Filipovska

Brief description Mitochondrial diseases are a diverse group of progressive and debilitating disorders for which there are no effective treatments. Furthermore it is currently impossible to apply gene therapy or RNA interference approaches to understand how mitochondria function or to treat mitochondrial diseases. We are developing a new technology that makes it possible to rationally manipulate mammalian mitochondrial RNAs for the first time, providing a unique approach for mitochondrial disease therapies.

Funding Amount $AUD 456,836.84

Funding Scheme Project Grants

Notes Standard Project Grant

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