Targeting mitochondrial metabolism in Diffuse Intrinsic Pontine Gliomas as a novel therapeutic strategy [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr David Ziegler (Principal investigator) ,  A/Pr Andrew Kung ,  Prof Philip Hogg

Brief description Diffuse Intrinsic Pontine Glioma (DIPG) represents the most aggressive cancer of childhood, with no effective treatments available, and almost all children dying within one year of diagnosis. We have successfully grown the first DIPG cells in the laboratory and found a new approach to attack them, by specifically targeting the cell's power source - the mitochondria. We will build on these findings and develop this treatment strategy with the aim to make this novel therapy available to children with this deadly disease.

Funding Amount $AUD 607,796.40

Funding Scheme Project Grants

Notes Standard Project Grant