Targeting microRNA-driven mesenchymal to epithelial transition to suppress prostate cancer metastasis [ 2015 - 2017 ]

Research Grant

Researchers: Dr Luke Selth (Principal investigator) ,  Dr Brett Hollier ,  Dr Philip Gregory ,  Prof Gregory Goodall ,  Prof Wayne Tilley

Brief description Prostate cancer kills ~3,000 men per year in Australia. The development of metastasis is the major cause of prostate cancer-associated death and has limited treatment options. In this study, we will characterise the role of a group of molecules, termed microRNAs, in prostate cancer metastasis. We will also test whether targeting microRNAs using novel drugs termed antagomiRs is an effective strategy to inhibit metastasis and thereby improve prostate cancer mortality.

Funding Amount $AUD 741,831.52

Funding Scheme Project Grants

Notes Standard Project Grant