Targeting microRNA-200b in diabetic nephropathy using two novel delivery systems [ 2016 - ]

Research Grant

Researchers: Dr Chunling Huang (Principal investigator)

Brief description Better treatments to prevent diabetic kidney disease are prioritized by government, commercial and philanthropic sectors. MicroRNA-based strategies limit kidney fibrosis in animal models of non-diabetic kidney disease. However, current delivery systems require optimization prior to human use. We have shown that microRNA-200b suppresses kidney fibrosis. We will study two delivery systems to deliver microRNA-200b to the kidney and to study its potential to prevent or limit diabetic kidney disease.

Funding Amount $314,644.00

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF