Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/116501]Researchers: Karin Eidne (Principal investigator)
Brief description We know that nutrition and reproduction are closely linked e.g. undernutrition leads to infertility, menopause to weight gain, but we do not know precisely the mechanisms whereby these events occur. The brain hormone gonadotropin-releasing hormone (GnRH), which stimulates the reproductive pathways and a recently discovered family of hormones (orexins) which stimulate feeding both act through the same type of recognition site i.e. G-protein coupled receptors (GPCRs) which are distributed in close proximity within the brain. Identifying how these two pathways interact has enormous potential for the treatment of disorders of weight and-or reproduction since the GPCR structure and the route by which it signals lends itself to therapeutic intervention.
Funding Amount $AUD 438,625.87
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 116501
- PURL : https://purl.org/au-research/grants/nhmrc/116501
