Targeting G-quadruplex DNA as a novel therapeutic strategy for Alzheimer’s and Frontotemporal Dementia [ 2017 - ]

Research Grant

Researchers: Dr Nicole Smith (Principal investigator)

Brief description Dementia is the third leading cause of death in Australia and there is an urgent need to identify new ways of treating diseases that cause dementia. Our research is focused on targeting an unusual DNA structure in Alzheimer’s and Frontotemporal dementia (FTD). We will use a precision-targeted technology to better control formation of this DNA structure in disease-causing genes, allowing us to switch off the gene and hence stop disease progression for Alzheimer’s and FTD.

Funding Amount $720,144.00

Funding Scheme Boosting Dementia Research Initiative

Notes Boosting Dementia Research Leadership Fellowship