Targeting early cellular damage during secondary degeneration using nanosphere-based drug delivery [ 2012 - 2015 ]

Research Grant

Researchers: Prof Sarah Dunlop (Principal investigator) ,  A/Pr Killugudi Swaminatha-Iyer ,  A/Pr Livia Hool ,  Prof Melinda Fitzgerald

Brief description After brain injury, there are no treatments to stop the spread of damage to intact tissue, a process involving different cell types and biochemical events. Clinical trials have targeted one event and have failed because large therapeutic doses are toxic and because combined treatments are needed to target different events. We will harness nanotechnology to target delivery of small, sustained doses of one or more drugs to specific cell types and biochemical events to stop the spread of damage.

Funding Amount $AUD 424,407.42

Funding Scheme Project Grants

Notes Standard Project Grant