Targeting the canonical Wnt signalling pathway to promote central nervous system remyelination in vivo [ 2016 - ]

Research Grant

Researchers: Dr David Gonsalvez (Principal investigator)

Brief description Multiple Sclerosis (MS) occurs when immune cells attack the sheaths, called myelin, that cover and protect nerve connections. If myelin is damaged nerve cells cannot function properly, leading to severe disability. The brain has a group of cells that could potentially replace damaged myelin, but as MS worsens these cells are blocked in a state where they cannot help in repair. I will remove a signal specifically from these cells and determine if this unblocks them resulting myelin repair.

Funding Amount $314,644.00

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF