grant

Targeting cancer-initiating cells with DNA methyltransferase inhibitors: single-cell analysis to decipher molecular mechanisms and improve efficacy. [ 2018 - 2019 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1143614]

Researchers: Dr Heather Lee (Principal investigator)

Brief description Certain cancer cells, termed cancer-initiating cells (CICs), have special properties allowing them to drive cancer growth and disease progression. These cells are particularly sensitive to low-dose treatment with drugs called DNA methyltransferase inhibitors. Using cutting-edge "single-cell" technologies this project will determine how these drugs target CICs and identify new ways to increase treatment efficacy. This work will identify new clinical opportunities for prevention of cancer relapse.

Funding Amount $AUD 177,450.00

Funding Scheme Project Grants

Notes New Investigator Grant

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Identifiers
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ACN 633 798 857