grant

Targeting bone marrow mediated angiogenesis and metastasis in breast cancer [ 2011 - 2017 ]

Also known as: EPCs and breast cancer metastasis

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1011114]

Researchers: A/Pr Albert Mellick (Principal investigator) ,  A/Pr Vivek Mittal Dr Christopher Day Prof Ming Wei

Brief description Despite advances in treatment and diagnostics breast cancer (BC) remains one of the leading causes of death in women. Metastases and tumour blood vessel recruitment are linked. Work by Dr Mellick and others has shown that host bone marrow contributes endothelial progenitor cells (EPCs) to tumour vasculature. The chemokines and their receptors, which differentiate EPCs from tumour vessels, will be knocked down in the tumour cells and EPC progenitors with the aim of preventing tumour spread.

Funding Amount $AUD 463,006.56

Funding Scheme Project Grants

Notes Standard Project Grant

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