Targeting antigen to Clec9A on dendritic cell for humoral immunity [ 2017 - ]

Research Grant

Researchers: Prof William Heath (Principal investigator) ,  A/Pr Irina Caminschi ,  A/Pr Scott Mueller

Brief description Dendritic cells capture infectious organisms and display them to other immune cells to initiate immunity. The process of capturing organisms requires dendritic cells to express a variety of cell-surface receptors that detect components carried by infectious agents. Here we will examine the efficacy of attaching vaccine components to a targeting agent that binds one of these receptors with the aim of enabling dendritic cells to efficiently kick-start immunity against vaccine components.

Funding Amount $744,624.00

Funding Scheme Project Grants

Notes Standard Project Grant