Targeting an ion pump in the malaria parasite with multiple compound classes [ 2013 - 2015 ]

Research Grant

Researchers: Prof Kiaran Kirk (Principal investigator) ,  The Australian National University (Managed by)

Brief description Large-scale antimalarial drug screening projects have identified three different classes of compound that kill the malaria parasite at extremely low doses and which hold real promise as next-generation antimalarials. Genetic evidence, as well as preliminary data from our own lab, has led us to the hypothesis that all three compound classes exert their antimalarial effect by blocking a molecular ion pump on the parasite surface. The aim of this study is to test this.

Funding Amount $AUD 384,686.75

Funding Scheme Project Grants

Notes Standard Project Grant