Targeting Adaptive Mechanisms to Endoplasmic Reticulum Stress in Melanoma [ 2009 - 2013 ]

Research Grant

Researchers: Prof Xu Dong Zhang (Principal investigator) ,  Dr Rick Thorne ,  Prof Peter Hersey

Brief description Melanoma is a major Australian health problem, but there is no curative treatment once the disease spreads beyond the skin. We will study the role the response of melanoma cells to stress conditions of an organelle called endoplasmic reticulum in determining sensitivity of melanoma to killing induced by therapeutic drugs. If successful, this study will provide much needed new insights into the resistance of melanoma to treatment and point to new treatment approaches against the disease.

Funding Amount $AUD 511,294.64

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant