grant

Targeted knockdown of human SOD1 genes by non-viral gene delivery to delay onset and progression of ALS [ 2008 - 2010 ]

Also known as: Targeting genes into diseased motor neurons

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/480404]

Researchers: E/Pr Robert Rush (Principal investigator)

Brief description Amyotrophic lateral sclerosis (ALS) is an illness of nerves resulting in a creeping paralysis and death; there is no effective treatment. We have developed immunogenes consisting of an antibody to target specific nerves and a gene that can affect it. Our immunogene will deliver genes that inhibit a mutant protein causing disease in an ALS mouse model. Successful outcomes of this research will be to encourage development of treatments both before and after the disease has developed.

Funding Amount $AUD 504,097.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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