Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1006487]Researchers: Prof Michelle Haber (Principal investigator) , A/Pr David Ziegler , Prof Murray Norris
Brief description The childhood cancer, neuroblastoma, frequently has a dismal outcome despite the use of intensive therapy. Polyamines are molecules that are essential for cell survival and these are increased in aggressive neuroblastoma. Using pre-clinical models, we have shown that inhibiting polyamine production can significantly delay neuroblastoma growth. This project aims to improve the overall efficacy of this treatment by targeting multiple steps in polyamine synthesis in combination with chemotherapy.
Funding Amount $AUD 576,605.57
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 1006487
- PURL : https://purl.org/au-research/grants/nhmrc/1006487
