Tailoring dendritic cell diversity to advance effective immunotherapies [ 1/1/2021 - 12/31/2025 ]

Research Grant

Brief description Dendritic cells (DCs) constitute the first line of defense against infection and cancer. To achieve this feat, DC have evolved into a sophisticated network of specialized subtypes, although how this diversification process occurs is yet to be fully clarified. We have uncovered a new molecule, termed DC-SCRIPT, which has a key role in establishing the DC network, specialization and function. This offers crucial new clues as to how to manipulate DCs to either boost or dampen the immune system.

Funding Amount $645,205

Funding Scheme Investigator Grants

Chief Investigator Dr Michael Chopin

Notes Emerging Leadership 1