Suppressor of cytokine signalling (SOCS4) is a critical regulator of the anti-viral immune response [ 2012 - 2014 ]

Research Grant

Researchers: Prof Katherine Kedzierska (Principal investigator) ,  Dr Jeffrey Babon ,  Dr Lukasz Kedzierski

Brief description The SOCS proteins are negative regulators of cytokine signalling and immune cell development and function. SOCS4 is the last remaining SOCS protein for which there is no described function or intracellular target. We intend to use well-defined acute and chronic viral disease models, and investigate the role of SOCS4 in infection in order to unravel its function. We will also search for its binding partners and intracellular targets, and determine the signalling pathways regulated by SOCS4.

Funding Amount $AUD 616,912.50

Funding Scheme Project Grants

Notes Standard Project Grant