Data

Summary of data analysis of RNAseq of DMSO, MCT, LPS and MCT/LPS treated rats

Flinders University
Carr, Jill
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.25451/flinders.30997291.v1&rft.title=Summary of data analysis of RNAseq of DMSO, MCT, LPS and MCT/LPS treated rats&rft.identifier=10.25451/flinders.30997291.v1&rft.publisher=Flinders University&rft.description=Laboratory models of lung disease often apply a stimulus to a healthy animal, which does not really mimic the complexity of human disease. The model here describes that prior stimulus with a chemical (MCT) - known to elicit progressive cardiovascular changes - predisposes to altered lung responses to a subsequent pathogen stimulus (LPS). This offers a laboratory model that incorporates the biological history of an animal, which impacts how the lung responds to a pathogen.The results here are described in the manuscript 10.64898/2025.12.21.695829. The raw data and metadata have been successfully uploaded to NCBI. The Bioproject Accession is: PRJNA1383992.&rft.creator=Carr, Jill &rft.date=2026&rft.edition=1&rft_rights= https://creativecommons.org/licenses/by-nc/4.0/&rft_subject=Other biological sciences not elsewhere classified&rft_subject=lung inflammation&rft_subject=monocrotaline&rft.type=dataset&rft.language=English Access the data
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Laboratory models of lung disease often apply a stimulus to a healthy animal, which does not really mimic the complexity of human disease. The model here describes that prior stimulus with a chemical (MCT) - known to elicit progressive cardiovascular changes - predisposes to altered lung responses to a subsequent pathogen stimulus (LPS). This offers a laboratory model that incorporates the biological history of an animal, which impacts how the lung responds to a pathogen.

The results here are described in the manuscript 10.64898/2025.12.21.695829. The raw data and metadata have been successfully uploaded to NCBI. The Bioproject Accession is: PRJNA1383992.

Issued: 05 01 2026

Created: 05 01 2026

Modified: 05 01 2026

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Other biological sciences not elsewhere classified | lung inflammation | monocrotaline |

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