grant

Sulfonadyn-based dynamin I-specific inhibitors and epilepsy [ 2011 - 2013 ]

Also known as: Improved potency of a novel type of antiepileptic drug called sulfonadyn

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1011457]

Researchers: Prof Phillip Robinson (Principal investigator) ,  Prof Adam Mccluskey

Brief description Epilepsy affects 1% of people, yet 30% do not respond to anti-epileptic drugs (AEDs). Traditional drug discovery fails to improve this situation. Our team discovered dynamin as a new target for better AED design and our lead sulphonadyns reduces seizures in animals. We will design better sulfonadyns that can ultimately be used for clinical trials by designing the drugs away from its actions outside of neurons. If successful, this will accelerate new AED development with less side-effects.

Funding Amount $AUD 835,291.82

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857