A subphenotyping approach to identifying genes responsible for isolated clefts of the lip and palate. [ 2010 - 2013 ]

Research Grant

Researchers: A/Pr Nicky Kilpatrick (Principal investigator) ,  Prof Ravi Savarirayan (Principal investigator) ,  Dr Astanand Jugessur ,  Prof Jeff Murray ,  Prof Mary Marazita

Brief description Clefts of the lip and palate are the most common birth defects involving the face. The genes responsible for these conditions have been difficult to find in the past. We have identified a method through which the chances of finding these genes is greatly increased. Detailed measurements of a number of facial features in cleft patients and unaffected first-degree relatives will provide a much clearer picture of those at higher risk of being affected by this debilitating disorder.

Funding Amount $AUD 679,707.17

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant