grant

Subcellular trafficking of P proteins of human pathogenic viruses: roles in viral pathogenicity and targeting for therapeutics [ 2011 - 2014 ]

Also known as: Viral escape from the immune system: targeting for therapy

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1003244]

Researchers: Dr Gregory Moseley (Principal investigator)

Brief description In order to infect humans, pathogenic viruses such as rabies, Nipah, Hendra and Australian bat lyssavirus must be able to evade the immune response. To do this, viruses produce "interferon antagonists" that interfere with specific immune processes by mechanisms that are not fully understood. Our study will characterise the mechanisms used by rabies and other viruses to block immunity, and identify strategies to disable viral immune evasion, rendering these lethal viruses susceptible to destruction by the human immune system.

Funding Amount $AUD 578,351.99

Funding Scheme Project Grants

Notes New Investigator Grant

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