Data

Study of Ketamine for Youth Depression (SKY-D)

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Daglas-Georgiou, Rose ; Mental Health Node
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.26187/NB86-SD54&rft.title=Study of Ketamine for Youth Depression (SKY-D)&rft.identifier=http://doi.org/10.26187/NB86-SD54&rft.publisher=Orygen&rft.description=The primary aim of this research project is to determine if a 4-week course of low-dose subcutaneous ketamine is an effective treatment for young people (males and females aged 16-25 years) with moderate-to-severe depression. Participants will be randomised to receive either low-dose subcutaneous ketamine or a blinded control treatment that is therapeutically inactive (midazolam), given once a week for 4 weeks. Change in depression scores will be assessed at the end of the treatment phase at week 4, with further assessment at weeks 8 and 26 to assess whether treatment effects are sustained. It is hypothesised that ketamine will be an effective treatment for moderate-to-severe depression in young people.&rft.creator=Daglas-Georgiou, Rose &rft.creator=Mental Health Node &rft.date=2025&rft.relation=https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=ACTRN12619000683134&rft.type=dataset&rft.language=English Access data via landing page

Full description

The primary aim of this research project is to determine if a 4-week course of low-dose subcutaneous ketamine is an effective treatment for young people (males and females aged 16-25 years) with moderate-to-severe depression. Participants will be randomised to receive either low-dose subcutaneous ketamine or a blinded control treatment that is therapeutically inactive (midazolam), given once a week for 4 weeks. Change in depression scores will be assessed at the end of the treatment phase at week 4, with further assessment at weeks 8 and 26 to assess whether treatment effects are sustained. It is hypothesised that ketamine will be an effective treatment for moderate-to-severe depression in young people.

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Identifiers
ACN 633 798 857