grant

Studies on the pathogenesis of human pterygia [ 2000 - 2002 ]

Also known as: Eye disease caused by UV light

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/113905]

Researchers: Prof Denis Wakefield (Principal investigator)

Brief description Pterygia, one of the most common ocular complaints in Australia and worldwide, are thought to originate from overexposure to UV light. We propose that UV-irradiation stimulate certain cells in the eye to produce cytokines, growth factors and enzymes which degrade scaffold proteins such as collagens. These enzymes may play a key role in the progressive and invasive nature of pterygia. Dissecting the mechanism(s) by which UV light induces these proteins will lead to new and more reliable therapies for the treatment of pterygia.

Funding Amount $AUD 204,972.28

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857