Structure-based design of inhibitors of oxidative protein folding in Enterobacteriaceae. [ 2011 - 2013 ]

Research Grant

Researchers: Prof Martin Scanlon (Principal investigator) ,  Dr Begona Heras ,  Dr Jamie Simpson ,  Prof William Charman

Brief description Antibiotic resistance represents a major public health problem. For gram-negative bacteria in particular, the situation is increasingly bleak, with the accumulation of resistance to existing drugs and few if any new drugs in the pipeline. We are using structure-based drug design to develop novel strategies for the treatment of gram-negative bacterial infections.

Funding Amount $AUD 523,540.13

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant