A structural understanding of class B G protein-coupled receptor function [ 2017 - ]

Research Grant

Researchers: Prof Patrick Sexton (Principal investigator) ,  Dr Sebastian Furness ,  Prof Brian Kobilka ,  Prof Georgios Skiniotis

Brief description G protein-coupled receptors (GPCRs) are the largest family of cell surface proteins that enable communication from external signals to the inside of cells of the body. Class B GPCRs are a therapeutically important subclass of these receptors and they play crucial roles in bone and energy homeostasis, cardiovascular control and immune response. This grant will uncover fundamental knowledge on how these receptors work, and will enhance future development of therapeutics.

Funding Amount $1,289,570.00

Funding Scheme Project Grants

Notes Standard Project Grant