Structural studies of the Jak and Abl kinases: a prerequisite for drug design [ 2004 - 2008 ]

Research Grant

Researchers: Dr Isabelle Lucet (Principal investigator)

Brief description Protein tyrosine kinases (PTK) are a large, pivotal family of signalling molecules implicated in diseases such as cancer and immune related disorders. This fellowship aims to develop more potent kinase inhibitors of a number of PTKs using Cytopia’s drug discovery capability coupled with the X-ray crystallography expertise within Monash University. This innovative approach will permit a rational structure-based drug discovery platform to be established and will lead to the creation of a portfolio of phase I therapeutics, which will be of substantial benefit in the medical health area.

Funding Amount $AUD 360,965.00

Funding Scheme Early Career Fellowships

Notes Industry ECF